Please join us for the upcoming PFN seminar on Wednesday, April 2, 2025 (3:30-4:30 pm). We are excited to welcome Henning Fenselau, PhD, from the Max Planck Institute for Metabolism Research for his talk titled: Opioid Regulation of Sugar Appetite Beyond Satiety. The seminar will be held in Gilmer Commons Room 490.
Opioid Regulation of Sugar Appetite Beyond Satiety
Satiety is a critical neurobiological process that diminishes eating when energy stores are full. However, although overall food intake is attenuated in states of satiety, it is directly associated with an increased desire to eat sweet, high sugar-containing foods (e.g., as dessert). The mechanisms that explain why sugar appetite is selectively stimulated in satiety states remain unclear. In this seminar, I will discuss our finding that the brain’s principal regulator of satiety – POMC neurons – not only decrease food intake through melanocortin signaling when energy stores are full, but at the same time give rise to an opioid signal that stimulates sugar appetite.
This seminar is open to the public.
Wednesday, April 2nd, 2025 | 3:30 - 4:30 pm | Gilmer Commons Room 490
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